Charles Rodolphe Brupbacher Prize

Biennially, the Foundation bestows the Charles Rodolphe Brupbacher Prize for Cancer Research upon a scientist who has made extraordinary contributions to basic oncological research.
The Prize ceremony takes place within the framework of a Scientific Symposium, which includes the Charles Rodolphe Brupbacher Public Lecture.

Laureate 2019

Prof. Dr. Michael N. Hall
University of Basel
Basel, Switzerland
mTOR signaling in growth and metabolism





Michael N. Hall

Laureate 2017

Prof. Sir Adrian Peter Bird
University of Edinburgh
Edinburgh, United Kingdom
DNA methylation patterns and cancer (pdf)

Prof. Dr. Laurence Zitvogel
Gustave Roussy Cancer Center
Paris, Frankreich
The role of immunogenic cell death and the gut microbiota in cancer treatment (pdf)

Prof. Dr. Guido Kroemer
Université Paris Descartes
Paris, Frankreich
Cancer cell stress and death - cell-autonomous and immunological considerations (pdf)

From left: Michael O. Hengartner (Rector of the University of Zurich), Sir Adrian Bird, Laurence Zitvogel, Guido Kroemer, Georg C. Umbricht (President of the Foundation Board)

Laureates 2015

Prof. Dr. Irving L. Weissman
Institute for Stem Cell Biology and Regenerative Medicine, Stanford University
Stanford, California, USA
The view from stem cell land: Stem cell biology in regeneration and cancer (pdf)

Prof. Dr. Joan Massagué
Sloan Kettering Institute
Memorial Sloan Kettering Cancer Center
New York, USA
Molecular Basis of Metastasis (pdf)

Top (from left): Dr. Klaus W. Grätz (Dean of the Medical Faculty), Dr. Irving L. Weissman, Georg C. Umbricht (Foundation Board) Below (from left): Dr. Klaus W. Grätz, Dr. Joan Massagué, Georg C. Umbricht

Laureate 2013

Prof. Dr. Michael Karin
Department of Pharmacology
University of San Diego
La Jolla, California, USA
Inflammation and Cancer: Effects, Mechanisms and Therapeutic Implications (pdf) 

From left: Georg C. Umbricht (Member of the Foundation Board), Dr. Michael Karin, Klaus W. Grätz (Dean of the Medical Faculty)

Laureates 2011

Prof. Dr. Bert Vogelstein
Howard Hughes Medical Institute
The Johns Hopkins University
Baltimore, Maryland, USA
The genetic basis of human cancer and its implications for patient management (pdf)

Prof. Dr. Jan H. Hoeijmakers
Department of Genetics Erasmus Medical Center
Erasmus University
Rotterdam, The Netherlands  
DNA damage and its impact on cancer, aging and longevity (pdf)

From left: Klaus W. Grätz (Dean of the Medical Faculty), Prof. Dr. Bert Vogelstein, Mme Frédérique Brupbacher (Founder), Prof. Dr. Jan H. Hoeijmakers, Prof. Dr. Andreas Fischer

Laureates 2009

Dr. Nubia Muñoz
International Agency for Research on Cancer (IARC) emerit. Wissenschaftlerin
Lyon, France  
From causality to prevention: The case of cervial cancer (pdf)

Prof. Sir Richard Peto
Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU)
University of Oxford
Oxford, United Kingdom  
The absolute benefits of anti-cancer drugs and of tobacco control (pdf)

From left: Prof. Sir Richard Peto, Dr. Nubia Muñoz

Laureates 2007

Prof. Dr. Lloyd J. Old
Ludwig Institute for Cancer Research
New York, USA  
Contributions to the Field of Cancer Immunology (pdf)

Prof. Dr. Robert D. Schreiber
Department of Pathology and Immunology
Washington University,
School of Medicine
St. Louis, Missouri, USA  
Cancer Immunoediting: Deciphering the Complex Interaction Between Immunity and Developing Tumors (pdf)

Prof. Dr. Mark J. Smyth
Cancer Immunology Program
Peter MacCallum Cancer Centre
East Melbourne, Victoria, Australia
Extrinsic tumor suppression by innate and adaptive immunity (pdf)

From left: Prof. Dr. Mark J. Smyth, Mme Frédérique Brupbacher (Founder), Prof. Dr. Robert D. Schreiber, Prof. Dr. Lloyd J. Old, Dr. Hans Erhart Brunner (Scientific Advisory Board)

Laureates 1993-2005

Prof. Dr. Mariano Barbacid
Centro Nacional de Investigaciones Oncologicas
Madrid, Spain   

The Molecular Bases of Human Cancer: a 25 Year Journey

Prof. Dr. Klaus Rajewsky
The CBR Institute for Biomedical Research
Harvard Medical School
Boston, MA, USA    The Janus Face of Antibody Formation:
Protective Function and Tumor Risk
Prof. Dr. Rudolf Jaenisch
Whitehead Institute for Biomedical Research, MIT
Cambridge, MA, USA   

Nuclear Cloning and the Reversibility of Cancer

Prof. Dr. Erwin Wagner
Institute of Molecular Pathology
Vienna, Austria   

Unravelling the Functions of AP-1 (Fos/Jun) in Mouse Development and Disease
Prof. Dr. Brian Druker
Oregon Health Sciences University
Portland, Oregon, USA   

Clinical and Basic Oncology: New Developments
Prof. Dr. George Klein
Microbiology and Tumor Biology Center (MTC)
Karolinska Institute
Stockholm, Sweden   

Cancer and the New Biology

Prof. Dr. Harald zur Hausen
Deutsches Krebsforschungzentrum
Heidelberg, Germany   

Cancer Causation by Viruses

Prof. Dr. Laurent Degos
Institut Universitaire d'Hématologie
Hôpital Saint Louis
Paris, France   

Differentiation Therapy of Cancer

Prof. Dr. Zhen-yi Wang
Shanghai Institute of Hematology
Rui-Jin Hospital
Shanghai Second Medical University
Shanghai, PR China   

Treatment of Acute Promyelocytic Leukemia with All-Trans Retinoic Acid: A Model of Differential Therapy in Cancer
Prof. Dr. Alfred G. Knudson
Fox Chase Cancer Center
Philadelphia, PA, USA   

Hereditary Cancer

Prof. Dr. Robert A. Weinberg
Whitehead Institute for Biomedical Research, Rui-Jin Hospital
Department of Biology, MIT
Cambridge, MA, USA   

Genes and Cancer
Prof. Dr. Arnold J. Levine
Department of Molecular Biology
Lewis Thomas Laboratory
Princeton University
Princeton, N.J., USA   

Functions of the p53 Gene and Protein

Prof. Dr. David P. Lane
Cancer Research Campaign Laboratories
Department of Biochemistry
University of Dundee
Dundee, Scotland   

The p53 Pathway, Past and Future